Genome-wide association study identifies three new melanoma susceptibility loci

Jennifer H. Barrett, Mark M. Iles, Mark Harland, +71

Nature Genetics

Genome-wide Association StudyGeneticsMelanomaGenetic EpidemiologyGenomics +2

High risk of tobacco-related cancers in <i>CDKN2A</i> mutation-positive melanoma families

Hildur Helgadóttir, Veronica Höiom, Göran Jönsson, +5

Journal of Medical Genetics

Targeting <scp>CDK</scp> 2 overcomes melanoma resistance against <scp>BRAF</scp> and Hsp90 inhibitors

Alireza Azimi, Stefano Caramuta, Brinton Seashore‐Ludlow, +13

Molecular Systems Biology

High Frequency of p16 Promoter Methylation in NRAS-Mutated Cutaneous Melanoma

Anders Jönsson, Rainer Tuominen, Eva Grafström, +2

Journal of Investigative Dermatology

Hereditary uveal melanoma: A report of a germline mutation in <i>BAP1</i>

Veronica Höiom, Daniel Edsgärd, Hildur Helgadóttir, +7

Genes Chromosomes and Cancer

Somatic VariantHereditary Uveal MelanomaGenetic DisorderExome SequencingGenetics +12

Germline<i>CDKN2A</i>Mutation Status and Survival in Familial Melanoma Cases

Hildur Helgadóttir, Veronica Höiom, Rainer Tuominen, +4

JNCI Journal of the National Cancer Institute

Germline CDKN2A mutations are rare in child and adolescent cutaneous melanoma

Peter A. Berg, Ann‐Marie Wennberg, Rainer Tuominen, +4

Melanoma Research

Somatic VariantSkin CancerMedicineGermline Cdkn2a MutationsPhotocarcinogenesis +10

MGMT promoter methylation is associated with temozolomide response and prolonged progression‐free survival in disseminated cutaneous melanoma

Rainer Tuominen, Rosalyn Jewell, Joost J. van den Oord, +12

International Journal of Cancer

Prognostic significance of tumor iNOS and COX-2 in stage III malignant cutaneous melanoma

C. Christian Johansson, Suzanne Egyházi, Giuseppe Masucci, +10

Cancer Immunology Immunotherapy

Skin CancerMedicineMelanomaPathologyPrognostic Significance +7

Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells

Alireza Azimi, Rainer Tuominen, Fernanda Costa Svedman, +10

Cell Death and Disease