Jeanine F. Amacher

A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

Adam H. Courtney, Jeanine F. Amacher, Theresa A. Kadlecek et al. · Molecular Cell · 2017 · 76 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Ziqing Qian, Xiaohua Xu, Jeanine F. Amacher et al. · Angewandte Chemie International Edition · 2015 · 75 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

A Compact Structure of Cytochrome <i>c</i> Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch

Jeanine F. Amacher, Fangfang Zhong, George P. Lisi et al. · Journal of the American Chemical Society · 2015 · 64 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses

Jeanine F. Amacher, Patrick R. Cushing, Lionel Brooks et al. · Structure · 2013 · 41 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains

Jeanine F. Amacher, Patrick R. Cushing, Christopher D. Bahl et al. · Journal of Biological Chemistry · 2012 · 40 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13