Daniel Filchtinski

Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes

Ina C. Rosnizeck, Thorsten Gräf, Michael Spoerner et al. · Angewandte Chemie International Edition · 2010 · 108 citations

What Makes Ras an Efficient Molecular Switch: A Computational, Biophysical, and Structural Study of Ras-GDP Interactions with Mutants of Raf

Daniel Filchtinski, Oz Sharabi, Alma Rüppel et al. · Journal of Molecular Biology · 2010 · 66 citations

Efficient Molecular Switch, Engineering, Makes Ras +9

Metal–Bis(2‐picolyl)amine Complexes as State 1(T) Inhibitors of Activated Ras Protein

Ina C. Rosnizeck, Michael Spoerner, Tobias Harsch et al. · Angewandte Chemie International Edition · 2012 · 64 citations

Computational Redesign of a Protein–Protein Interface for High Affinity and Binding Specificity Using Modular Architecture and Naturally Occurring Template Fragments

Vladimir Potapov, Dana Reichmann, Renne Abramovich et al. · Journal of Molecular Biology · 2008 · 48 citations

High Affinity, Biochemistry, Protein Assembly +8

Improved Binding of Raf to Ras·GDP Is Correlated with Biological Activity

Christina Kiel, Daniel Filchtinski, Michael Spoerner et al. · Journal of Biological Chemistry · 2009 · 47 citations · Full text