Lei Yang

Sintilimab versus placebo in combination with chemotherapy as first line treatment for locally advanced or metastatic oesophageal squamous cell carcinoma (ORIENT-15): multicentre, randomised, double blind, phase 3 trial

Zhihao Lü, Junye Wang, Yongqian Shu et al. · BMJ · 2022 · 480 citations · Full text

Medicine, Oncology, Pharmacotherapy +14

Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma

Meng Zhou, Hengqiang Zhao, Zhenzhen Wang et al. · Journal of Experimental & Clinical Cancer Research · 2015 · 181 citations · Full text

Life Sciences, Bioinformatics, Oncology +17

Clinical and biomarker analyses of sintilimab versus chemotherapy as second-line therapy for advanced or metastatic esophageal squamous cell carcinoma: a randomized, open-label phase 2 study (ORIENT-2)

Jianming Xu, Yi Li, Qingxia Fan et al. · Nature Communications · 2022 · 150 citations · Full text

Medicine, Oncology, Pharmacology +17

PseKRAAC: a flexible web server for generating pseudo K-tuple reduced amino acids composition

Yongchun Zuo, Yuan Li, Guangpeng Li et al. · Bioinformatics · 2016 · 147 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +10

A Comparison for Dimensionality Reduction Methods of Single-Cell RNA-seq Data

Ruizhi Xiang, Wencan Wang, Lei Yang et al. · Frontiers in Genetics · 2021 · 146 citations · Full text

Life Sciences, Bioinformatics, Cell Biology +16