Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes

Sedigheh Delmaghani, Jean Defourny, Asadollah Aghaie, +18

Cell

EngineeringAllergySound ExposurePhysiologyNoise Pollution +6

Increasing intracellular free calcium induces circumferential contractions in isolated cochlear outer hair cells

Didier Dulon, Gary Zajic, Jochen Schacht

Journal of Neuroscience

Acetylcholine-induced potassium current of guinea pig outer hair cells: its dependence on a calcium influx through nicotinic-like receptors

Christophe Blanchet, Carlos Eróstegui, Masashi Sugasawa, +1

Journal of Neuroscience

NeurotransmissionCellular PhysiologySocial SciencesCholinergic Efferent InhibitionHyperpolarization (Biology) +21

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

Nicolas Michalski, Juan D. Goutman, Sarah M. Auclair, +17

eLife

Otoferlin Is Critical for a Highly Sensitive and Linear Calcium-Dependent Exocytosis at Vestibular Hair Cell Ribbon Synapses

Didier Dulon, Saaïd Safieddine, Sherri M. Jones, +1

Journal of Neuroscience

Control of Exocytosis by Synaptotagmins and Otoferlin in Auditory Hair Cells

Maryline Beurg, Nicolas Michalski, Saaïd Safieddine, +5

Journal of Neuroscience

Rrp RecoveryVesicle ExocytosisNeurotransmissionIhc ExocytosisCellular Physiology +16

Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G

Alice Emptoz, Vincent Michel, Andrea Lelli, +15

Proceedings of the National Academy of Sciences

Clarin-1 gene transfer rescues auditory synaptopathy in model of Usher syndrome

Didier Dulon, Samantha Papal, Pranav Patni, +16

Journal of Clinical Investigation

Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells

Didier Dulon, Gary Zajic, J.‐M. Aran, +1

Journal of Neuroscience Research

Intracellular Calcium LevelsBiochemistryAntibioticsMedicineOuter Hair Cells +10

Calcium- and Otoferlin-Dependent Exocytosis by Immature Outer Hair Cells

Maryline Beurg, Saaïd Safieddine, Isabelle Roux, +3

Journal of Neuroscience