Natalie J. Spillman

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Jessica L. Bridgford, Stanley C. Xie, Simon A. Cobbold et al. · Nature Communications · 2018 · 294 citations · Full text

Na+ Regulation in the Malaria Parasite Plasmodium falciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

Natalie J. Spillman, Richard J. Allen, Case W. McNamara et al. · Cell Host & Microbe · 2013 · 238 citations · Full text

Antiparasitic Agent, Malaria, Molecular Biology +17

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of <i>Plasmodium</i>

Marı́a Belén Jiménez-Dı́az, Daniel Ebert, Yandira G. Salinas et al. · Proceedings of the National Academy of Sciences · 2014 · 238 citations · Full text

Phenotypic Screening, Antiparasitic Agent, Malaria +17

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

Akhil B. Vaidya, Joanne M. Morrisey, Zhongsheng Zhang et al. · Nature Communications · 2014 · 131 citations · Full text

Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking

Kit Kennedy, Simon A. Cobbold, Eric Hanssen et al. · PLoS Biology · 2019 · 117 citations · Full text

Antiparasitic Agent, Malaria, Immunology +17