Christopher Böhm

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Ekaterina Rogaeva, Yan Meng, Joseph H. Lee et al. · Nature Genetics · 2007 · 1.2K citations · Full text

Molecular Neuroscience, Alzheimer's Disease, Dementia +13

TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity

Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt‐Ulms et al. · Nature · 2006 · 296 citations

Protein Secretion, Signal Transduction, ɛ-Secretase Activity +9

Coding mutations in <scp><i>SORL</i></scp><i>1</i> and <scp>A</scp>lzheimer disease

Badri N. Vardarajan, Yalun Zhang, Joseph H. Lee et al. · Annals of Neurology · 2014 · 179 citations · Full text

ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism

Tetsuro Murakami, Seung‐Pil Yang, Lin Xie et al. · Human Molecular Genetics · 2011 · 121 citations · Full text

Mutant Fus, Amyotrophic Lateral Sclerosis, Developmental Biology +14

<i>SORL1</i> mutations in early- and late-onset Alzheimer disease

Michael L. Cuccaro, Regina M. Carney, Yalun Zhang et al. · Neurology Genetics · 2016 · 77 citations · Full text