Yutaka Umayahara

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.

Hideaki Kaneto, Yoshitaka Kajimoto, J Miyagawa et al. · Diabetes · 1999 · 711 citations

Lipid Peroxidation, Antioxidant Treatment, Insulin Signaling +18

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

Hiddo J.L. Heerspink, Hans‐Henrik Parving, Dennis L. Andress et al. · The Lancet · 2019 · 589 citations · Full text

Urology, Renal Disease, Renal Events +7

Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer.

Yutaka Umayahara, Ryuzo Kawamori, Hirotaka Watada et al. · Journal of Biological Chemistry · 1994 · 389 citations · Full text

Genetics, Insulin Signaling, Mammary Gland Development +21

Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells.

T Matsuoka, Yoshitaka Kajimoto, Hirotaka Watada et al. · Journal of Clinical Investigation · 1997 · 358 citations · Full text

The Human Glucokinase Gene β-Cell-Type Promoter: An Essential Role of Insulin Promoter Factor 1/PDX-1 in Its Activation in HIT-T15 Cells

Hirotaka Watada, Yoshitaka Kajimoto, Yutaka Umayahara et al. · Diabetes · 1996 · 220 citations

Immunology, Immune Regulation, Molecular Biology +22