Michele Kubryk

Highly Efficient Asymmetric Synthesis of Sitagliptin

Karl B. Hansen, Yi Hsiao, Feng Xu et al. · Journal of the American Chemical Society · 2009 · 308 citations

Pharmacy, Biochemistry, Medicinal Chemistry +12

First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

Karl B. Hansen, Jaume Balsells, Spencer D. Dreher et al. · Organic Process Research & Development · 2005 · 162 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Remote Desymmetrization at Near-Nanometer Group Separation Catalyzed by a Miniaturized Enzyme Mimic

Chad A. Lewis, Anna Chiu, Michele Kubryk et al. · Journal of the American Chemical Society · 2006 · 86 citations

Engineering, Chemical Engineering, Chemistry +17

Scalable, efficient process for the synthesis of (R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex

Karl B. Hansen, Jennifer R. Chilenski, Richard Desmond et al. · Tetrahedron Asymmetry · 2003 · 80 citations

Natural Sciences, Chemical Engineering, Chemistry +12

Synthesis of [1,2,4]Triazolo[4,3-α]piperazines via Highly Reactive Chloromethyloxadiazoles

Jaume Balsells, Lisa DiMichele, Michele Kubryk et al. · Organic Letters · 2005 · 56 citations

Natural Sciences, Chemistry, Medicinal Chemistry +4