Paul Scullion

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

Anup Aggarwal, Maloy Kumar Parai, N.D. Shetty et al. · Cell · 2017 · 182 citations · Full text

Pharmacy, Chemistry, Molecular Biology +12

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Beatriz Baragaña, Barbara Forte, Ryan Choi et al. · Proceedings of the National Academy of Sciences · 2019 · 139 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

Dhaval Varshney, Alain‐Pierre Petit, Juan A. Bueren‐Calabuig et al. · Nucleic Acids Research · 2016 · 81 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and <i>Mycobacterium tuberculosis</i>: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

Dinakaran Murugesan, Peter C. Ray, Tracy Bayliss et al. · ACS Infectious Diseases · 2018 · 76 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Lead Optimization of a Pyrazole Sulfonamide Series of <i>Trypanosoma brucei</i> <i>N</i> -Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis

Stephen Brand, Neil R. Norcross, Stephen Thompson et al. · Journal of Medicinal Chemistry · 2014 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17