Allison Sheen

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

Yash Agarwal, Lauren E. Milling, Jason Y.H. Chang et al. · Nature Biomedical Engineering · 2022 · 136 citations · Full text

Medicine, Immunology, Oncology +14

Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies

Brianna M. Lax, Joseph R. Palmeri, Emi A. Lutz et al. · Proceedings of the National Academy of Sciences · 2023 · 53 citations · Full text

Life Sciences, Immunology, Oncology +17

Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies

Emi A. Lutz, Yash Agarwal, Noor Momin et al. · Proceedings of the National Academy of Sciences · 2022 · 31 citations · Full text

Life Sciences, Immunology, Oncology +17

Intratumoral nanobody–IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice

Emi A. Lutz, Noor Jailkhani, Noor Momin et al. · PNAS Nexus · 2022 · 30 citations · Full text

Life Sciences, Immunology, Oncology +17

Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2

Brendan Horton, Alicia D. D’Souza, Maria Zagorulya et al. · JCI Insight · 2023 · 25 citations · Full text

Life Sciences, Immunology, Oncology +17