Transcription factor AP-2 essential for cranial closure and craniofacial development

Hubert Schorle, Pascal Meier, Michael Büchert, +2

Nature

Developmental BiologyDevelopmental GeneticsGeneticsCraniofacial DevelopmentMorphogenesis +6

STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Matthias Ernst, Meri Najdovska, Dianne Grail, +13

Journal of Clinical Investigation

IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization

Moritz F. Eissmann, Christine D. Dijkstra, Andrew Jarnicki, +14

Nature Communications

The Junction-associated Protein AF-6 Interacts and Clusters with Specific Eph Receptor Tyrosine Kinases at Specialized Sites of Cell–Cell Contact in the Brain

Michael Büchert, Stefan Schneider, Virginia Meskenaïte, +5

The Journal of Cell Biology

ImmunologyCellular NeurobiologySynaptic SignalingCellular PhysiologySocial Sciences +18

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

Michael M. Halford, Jane E. Armes, Michael Büchert, +8

Nature Genetics

Knockout MouseDevelopmental BiologyMolecular PhysiologySignal TransductionSignaling Pathway +5

Defective Claudin-7 Regulation by Tcf-4 and Sox-9 Disrupts the Polarity and Increases the Tumorigenicity of Colorectal Cancer Cells

Charbel Darido, Michael Büchert, Julie Pannequin, +9

Cancer Research

mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice

Stefan Thiem, Thomas P. Pierce, Michelle Palmieri, +15

Journal of Clinical Investigation

InflammationCytokineMtor Complex 1Gastrointestinal OncologyMedicine +10

Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo

Michael Büchert, Dimitris Athineos, Helen E. Abud, +16

PLoS Genetics

DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma

Stéphanie Boireau, Michael Büchert, Michael S. Samuel, +10

Carcinogenesis

Cancer ResearchGenitourinary CancerTight JunctionPathologyCancer Genomics +9

Mutagenesis and selection of PDZ domains that bind new protein targets

Stefan Schneider, Michael Büchert, Oleg Georgiev, +6

Nature Biotechnology

Protein FunctionMolecular BiologyProtein ModelingNew Protein TargetsSystems Biology +1