Pernille Holm

Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP.

Kirsten Sandvig, Marie Ryd, Oslo Garred et al. · The Journal of Cell Biology · 1994 · 180 citations · Full text

Toxinology, Retrograde Transport, Molecular Biology +19

Multivesicular bodies in HEp-2 cells are maturing endosomes.

Bo van Deurs, Pernille Holm, Lars Kayser et al. · PubMed · 1993 · 154 citations

Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide

Jais Rose Bjelke, Lene Hansen, Lars C. Petersen et al. · Blood · 2011 · 136 citations · Full text

Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes.

Bo van Deurs, Pernille Holm, Lars Kayser et al. · PubMed · 1995 · 121 citations

Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells.

Bo van Deurs, Pernille Holm, Kirsten Sandvig · PubMed · 1996 · 104 citations