Leon van Haandel

The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response

Mara L. Becker, Roger Gaedigk, Leon van Haandel et al. · Arthritis & Rheumatism · 2010 · 71 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase

Li Q. Zhang, Leon van Haandel, Min Xiong et al. · Cell Death and Disease · 2017 · 69 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: Effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations

Mara L. Becker, Leon van Haandel, Roger Gaedigk et al. · Arthritis & Rheumatism · 2010 · 67 citations

Medicine, Pharmacokinetics, Pharmacology +10

Single dose, CYP2D6 genotype‐stratified pharmacokinetic study of atomoxetine in children with ADHD

JT Brown, SM Abdel‐Rahman, Leon van Haandel et al. · Clinical Pharmacology & Therapeutics · 2015 · 66 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

A novel high‐performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells

Leon van Haandel, Mara L. Becker, J. Steven Leeder et al. · Rapid Communications in Mass Spectrometry · 2009 · 44 citations

Pharmacy, Pharmaceutics, Pharmacology +17