Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

Antoni Hurtado, Kelly A. Holmes, Timothy R. Geistlinger, +7

Nature

Breast OncologyOestrogen Receptor–pax2MedicineHormonal ReceptorBreast Cancer +4

Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial

Andreas Polychronis, H D Sinnett, Dimitri Hadjiminas, +13

The Lancet Oncology

Breast OncologyMedicineGynecologyBreast CancerCancer Treatment +4

Transient Receptor Potential Melastatin 7–like Current in Human Head and Neck Carcinoma Cells: Role in Cell Proliferation

Jie Jiang, Minghua Li, Kōichi Inoue, +3

Cancer Research

The DEAD-box protein p72 regulates ERα-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERα-positive breast cancer

NC Wortham, Eliyaz Ahamed, Samantha M. Nicol, +10

Oncogene

Tumor BiologyTranscriptional RegulationBreast OncologySignaling PathwayMedicine +10

Phosphorylation of ERα at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERα phosphorylation in breast cancer progression

Naveed Sarwar, J. S. Kim, Jie Jiang, +9

Endocrine Related Cancer

Phosphorylation of Estrogen Receptor-α at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients

Jie Jiang, Naveed Sarwar, David Peston, +4

Clinical Cancer Research

Final results from the PERUSE study of first-line pertuzumab plus trastuzumab plus a taxane for HER2-positive locally recurrent or metastatic breast cancer, with a multivariable approach to guide prognostication

David Miles, Eva Ciruelos, Fabio Puglisi, +230

Annals of Oncology

Pathophysiologically Relevant Levels of Hydrogen Peroxide Induce Glutamate-Independent Neurodegeneration That Involves Activation of Transient Receptor Potential Melastatin 7 Channels

Emily Coombes, Jie Jiang, Xiang‐Ping Chu, +5

Antioxidants and Redox Signaling

Relevant LevelsGlutamate ReceptorsCellular PhysiologySocial SciencesOxidative Stress +20

Reproducibility of [11C]Choline-Positron Emission Tomography and Effect of Trastuzumab

Laura Kenny, Kaiyumars Contractor, Rainer Hinz, +7

Clinical Cancer Research

Mutant p53 driven-LINC00857, a protein scaffold between FOXM1 and deubiquitinase OTUB1, promotes the metastasis of pancreatic cancer

Weifan Zhang, Weikun Qian, Jingtao Gu, +11

Cancer Letters

Tumor BiologyMutant P53 Driven-linc00857Pancreatic CancerMedicineCancer Cell Biology +8