Sophie Chasset

Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage

Erwann Le Rouzic, Damien Bonnard, Sophie Chasset et al. · Retrovirology · 2013 · 125 citations · Full text

Structural Basis for <i>E. coli</i> Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design

Nicolas Lévy, Jean‐Michel Bruneau, Erwann Le Rouzic et al. · Journal of Medicinal Chemistry · 2019 · 43 citations · Full text

Drug Target, Molecular Biology, Penicillin-binding Proteins +19

Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration

Damien Bonnard, Erwann Le Rouzic, Sylvia Eiler et al. · Journal of Biological Chemistry · 2018 · 36 citations · Full text

Hiv-1 Integrase, Human Retrovirus, Immunology +10

The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity

Céline Amadori, Yme U. van der Velden, Damien Bonnard et al. · Retrovirology · 2017 · 22 citations · Full text

Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase

Damien Bonnard, Erwann Le Rouzic, Matthew R. Singer et al. · Antimicrobial Agents and Chemotherapy · 2023 · 10 citations · Full text