William M. Marsiglia

Structural basis for the action of the drug trametinib at KSR-bound MEK

Z.M. Khan, Alexander M. Real, William M. Marsiglia et al. · Nature · 2020 · 172 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ

Zhifeng Huang, William M. Marsiglia, Upal Roy et al. · Molecular Cell · 2015 · 58 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

Lingfeng Chen, William M. Marsiglia, Huaibin Chen et al. · Nature Chemical Biology · 2020 · 57 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +11

Defining Substrate and Blocker Activity of Alanine-Serine-Cysteine Transporter 2 (ASCT2) Ligands with Novel Serine Analogs

Thomas Albers, William M. Marsiglia, T. Darrah Thomas et al. · Molecular Pharmacology · 2011 · 52 citations · Full text

Pharmacy, Biochemistry, Pharmacology +17

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

Huaibin Chen, William M. Marsiglia, Min‐Kyu Cho et al. · eLife · 2017 · 49 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17