Olalla Sanz

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>

Yumi Park, A. Pacitto, Tracy Bayliss et al. · ACS Infectious Diseases · 2016 · 91 citations

Life Sciences, Molecular Biology, Pharmacology +13

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Manu Vanaerschot, James M. Murithi, Charisse Flerida A. Pasaje et al. · Cell chemical biology · 2020 · 91 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

Ca ²⁺ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG

Aurélia C. Balestra, Konstantinos Koussis, Natacha Klages et al. · Science Advances · 2021 · 71 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

GSK2556286 Is a Novel Antitubercular Drug Candidate Effective <i>In Vivo</i> with the Potential To Shorten Tuberculosis Treatment

Eric L. Nuermberger, Maria Santos Martínez, Olalla Sanz et al. · Antimicrobial Agents and Chemotherapy · 2022 · 48 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in <i>Mycobacterium tuberculosis</i> by the Novel Drug Candidate GSK2556286

Kirstin Brown, Kaley M. Wilburn, Christine R. Montague et al. · Antimicrobial Agents and Chemotherapy · 2023 · 32 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9