Stuart Lutzker

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

Gareth L. Bond, Wenwei Hu, Elisabeth E. Bond et al. · Cell · 2004 · 1.3K citations · Full text

Mdm2 Promoter, Single Nucleotide Polymorphism, Oncogenic Agent +10

Phase I Study of Trastuzumab-DM1, an HER2 Antibody-Drug Conjugate, Given Every 3 Weeks to Patients With HER2-Positive Metastatic Breast Cancer

Ian E. Krop, Muralidhar Beeram, Shanu Modi et al. · Journal of Clinical Oncology · 2010 · 590 citations

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

T. Keith Blackwell, Mark W. Moore, George D. Yancopoulos et al. · Nature · 1986 · 305 citations

Immunogenetics, Transcriptional Regulation, Protein Expression +8

Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching

Stuart Lutzker, Paul B. Rothman, Roberta R. Pollock et al. · Cell · 1988 · 275 citations

Transcriptional Regulation, Signal Transduction, Immune Cell Development +10

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

George D. Yancopoulos, Ronald A. DePinho, Kathy A. Zimmerman et al. · The EMBO Journal · 1986 · 220 citations · Full text

Genetics, Class Switching, Genomic Mechanism +7