Lea M. Hürlimann

Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

Michael Höhl, Lea M. Hürlimann, Simon Böhm et al. · Proceedings of the National Academy of Sciences · 2014 · 119 citations · Full text

Structural Bioinformatics, Molecular Biology, Apo Structure +16

The ABC exporter IrtAB imports and reduces mycobacterial siderophores

Fabian Arnold, Miriam S. Weber, Imre Gonda et al. · Nature · 2020 · 92 citations · Full text

Bacteriology, Microbiology, Reduces Mycobacterial Siderophores +1

The extracellular gate shapes the energy profile of an ABC exporter

Cedric A. J. Hutter, M. Hadi Timachi, Lea M. Hürlimann et al. · Nature Communications · 2019 · 82 citations · Full text

The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis

Lea M. Hürlimann, Valentina Corradi, Michael Höhl et al. · Antimicrobial Agents and Chemotherapy · 2016 · 53 citations · Full text

Medical Microbiology, Enterococcus Faecalis, Antimicrobial Susceptibility +13

Deep mutational scan of a drug efflux pump reveals its structure–function landscape

Gianmarco Meier, Sujani Thavarasah, Kai Ehrenbolger et al. · Nature Chemical Biology · 2022 · 46 citations · Full text

Drug Target, Medicine, Deep Mutational Scan +9