Harm Brugge

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Urmo Võsa, Annique Claringbould, Harm-Jan Westra et al. · Nature Genetics · 2021 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

Urmo Võsa, Annique Claringbould, Harm-Jan Westra et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 546 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs

Monique G.P. van der Wijst, Harm Brugge, Dylan H. de Vries et al. · Nature Genetics · 2018 · 462 citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Improving the diagnostic yield of exome- sequencing by predicting gene–phenotype associations using large-scale gene expression analysis

Patrick Deelen, Sipko van Dam, Johanna C. Herkert et al. · Nature Communications · 2019 · 151 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure

Roy Oelen, Dylan H. de Vries, Harm Brugge et al. · Nature Communications · 2022 · 126 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17