Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation

Joseph E. Chambers, Lucy E. Dalton, Hanna J. Clarke, +6

eLife

Molecular RegulationMolecular BiologyCytoskeletonPpp1r15 Family MembersCellular Physiology +18

EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

Nikola Holtkamp, Elke Malzer, Jan Zietsch, +6

Neuro-Oncology

Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme

Nikola Holtkamp, Nicolas Ziegenhagen, Elke Malzer, +3

Neuro-Oncology

Gene AmplificationEngineeringCytogeneticsGeneticsAmplification Status +16

Coordinate regulation of eIF2α phosphorylation by dPPP1R15 and dGCN2 is required during development

Elke Malzer, Małgorzata Szajewska-Skuta, Lucy E. Dalton, +6

Journal of Cell Science

p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress

Sally E. Thomas, Elke Malzer, A. Ordóñez, +6

Journal of Biological Chemistry

Cell RegulationCell DivisionNatural SciencesMolecular BiologyCell Death +6

Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response

Elke Malzer, Marie‐Louise Daly, Aileen M. Moloney, +7

Journal of Cell Science

Cell ProliferationEr StressCell CycleCellular PhysiologyTumor Biology +17

Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy

Matheus Henrique Dias, Anoek Friskes, Siying Wang, +35

Cancer Discovery

The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z‐α ₁ ‐antitrypsin

Jennifer A. Dickens, A. Ordóñez, Joseph E. Chambers, +9

The FASEB Journal

Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB

Benoit D. Roussel, Timothy Mark Newton, Elke Malzer, +8

Human Molecular Genetics

AgingMolecular BiologyNeurochemical BiomarkersCytoskeletonNeuroserpin Polymer Degradation +23

The integrated stress response regulates BMP signalling through effects on translation

Elke Malzer, Caia Dominicus, Joseph E. Chambers, +3

BMC Biology