Concepedia

Vanina Rea

VR

Statistics

Publications

5

Citations

142

H-Index

5

Active since

2011

Affiliations

Vrije Universiteit Amsterdam(Current)

Vanina Rea is an author at Vrije Universiteit Amsterdam specializing in pharmacology, cytochrome p450 enzymes, and drug-metabolizing enzymes.

Publications per year

2011–2012

5

Publications

5

Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11

Eduardo Vottero, Vanina Rea, Jeroen Lastdrager et al. · JBIC Journal of Biological Inorganic Chemistry · 2011 · 56 citations · Full text

, , +17

Active Site Substitution A82W Improves the Regioselectivity of Steroid Hydroxylation by Cytochrome P450 BM3 Mutants As Rationalized by Spin Relaxation Nuclear Magnetic Resonance Studies

Vanina Rea, A.J. Kolkman, Eduardo Vottero et al. · Biochemistry · 2011 · 44 citations

, , +17

Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates

Vanina Rea, Sanja Dragović, Jan Simon Boerma et al. · Drug Metabolism and Disposition · 2011 · 17 citations

, , +16

Combination of biotransformation by P450 BM3 mutants with on-line post-column bioaffinity and mass spectrometric profiling as a novel strategy to diversify and characterize p38α kinase inhibitors

Vanina Rea, David Falck, Jeroen Kool et al. · MedChemComm · 2012 · 14 citations

, , +16

The Role of Protein Plasticity in Computational Rationalization Studies on Regioselectivity in Testosterone Hydroxylation by Cytochrome P450 BM3 Mutants

Stephanie B. A. de Beer, Laura A. H. van Bergen, Karlijn Keijzer et al. · Current Drug Metabolism · 2012 · 11 citations

, , +17

1–5 of 5