Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells

Anna S. Monzel, Lisa M. Smits, Kathrin Hemmer, +11

Stem Cell Reports

Modeling Parkinson’s disease in midbrain-like organoids

Lisa M. Smits, Lydia Reinhardt, Peter Reinhardt, +18

npj Parkinson s Disease

Millifluidic culture improves human midbrain organoid vitality and differentiation

Emanuel Berger, Chiara Magliaro, Nicole Paczia, +6

Lab on a Chip

Cell CultureCerebral OrganoidOrgan-on-a-chipBiomedical EngineeringCellular Physiology +21

OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases

Gabriel Sturm, Kalpita R. Karan, Anna S. Monzel, +26

Communications Biology

Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease

Sarah Nickels, Jennifer Modamio, Bárbara Mendes-Pinheiro, +3

Stem Cell Research

Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality

Jonas Walter, Silvia Bolognin, Paul Antony, +16

Stem Cell Reports

Mitochondrial FunctionMedicineNeural Stem CellNeuroscienceNeurodegeneration +3

Machine learning-assisted neurotoxicity prediction in human midbrain organoids

Anna S. Monzel, Kathrin Hemmer, Tony Kaoma, +10

Parkinsonism & Related Disorders

Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by <scp>2‐Hydroxypropyl‐β‐Cyclodextrin</scp> Treatment

Javier Jarazo, Kyriaki Barmpa, Jennifer Modamio, +31

Movement Disorders

Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging

Natalia Bobba‐Alves, Gabriel Sturm, Jue Lin, +14

Psychoneuroendocrinology

A human brain map of mitochondrial respiratory capacity and diversity

Eugene V. Mosharov, Ayelet M Rosenberg, Anna S. Monzel, +19

Nature

BiologyMitochondrial FunctionNeurophysiologyNeuroanatomyMedicine +9