Björn Frahm

Improvement of a mammalian cell culture process by adaptive, model-based dialysis fed-batch cultivation and suppression of apoptosis

Björn Frahm, P.M. Lane, H. M�rkl et al. · Bioprocess and Biosystems Engineering · 2003 · 71 citations

Pharmacy, Bioengineering, Biotechnology +14

Adaptive, Model‐Based Control by the Open‐Loop‐Feedback‐Optimal (OLFO) Controller for the Effective Fed‐Batch Cultivation of Hybridoma Cells

Björn Frahm, Paul Lane, Hendrik Atzert et al. · Biotechnology Progress · 2002 · 64 citations

Life Sciences, Bioengineering, Biotechnology +16

Determination of dissolved CO2 concentration and CO2 production rate of mammalian cell suspension culture based on off-gas measurement

Björn Frahm, Heinz-Christian Blank, Peter Cornand et al. · Journal of Biotechnology · 2002 · 63 citations

Life Sciences, Biotechnology, Cell Biology +14

Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes

Johannes Möller, Tanja Hernández Rodríguez, Jan Müller et al. · Computers & Chemical Engineering · 2019 · 45 citations · Full text

Business, Bioengineering, Biopharmaceutics +15

A biocatalytic cascade reaction sensitive to the gas–liquid interface: Modeling and upscaling in a dynamic membrane aeration reactor

Wouter Van Hecke, Dietmar Haltrich, Björn Frahm et al. · Journal of Molecular Catalysis B Enzymatic · 2010 · 43 citations

Engineering, Biotechnology, Chemical Engineering +16