Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

Manuela Molzan, Benjamin Schumacher, Corinna Ottmann, +11

Molecular and Cellular Biology

Crystal StructureImmunologyNew ApproachesPathologyMolecular Biology +17

Regulation of RAF Activity by 14-3-3 Proteins

Andreas Fischer, Angela Baljuls, Jörg Reinders, +7

Journal of Biological Chemistry

Identification of Novel in Vivo Phosphorylation Sites of the Human Proapoptotic Protein BAD

Lisa Polzien, Angela Baljuls, Ulrike Rennefahrt, +9

Journal of Biological Chemistry

ApoptosisProteasomeMolecular BiologyCell DeathSignaling Pathway +18

Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells

Carmen Sanges, C Scheuermann, René P. Zahedi, +11

Cell Death and Disease

Positive Regulation of A-RAF by Phosphorylation of Isoform-specific Hinge Segment and Identification of Novel Phosphorylation Sites

Angela Baljuls, Werner Schmitz, Thomas D. Mueller, +4

Journal of Biological Chemistry

Amino Acids 248Molecular RegulationMolecular BiologySignaling PathwayCell Regulation +15

Unique N-region Determines Low Basal Activity and Limited Inducibility of A-RAF Kinase

Angela Baljuls, Thomas D. Mueller, Hannes C. A. Drexler, +2

Journal of Biological Chemistry

Molecular RegulationMolecular BiologyGlycine 300Chemical BiologyA-raf Kinase +16

Single Substitution within the RKTR Motif Impairs Kinase Activity but Promotes Dimerization of RAF Kinase

Angela Baljuls, Regina Mahr, Inge Schwarzenau, +4

Journal of Biological Chemistry

Serine/threonine Kinase RafMolecular RegulationMolecular BiologyMapk CascadePromotes Dimerization +17

BAD Contributes to RAF-mediated Proliferation and Cooperates with B-RAF-V600E in Cancer Signaling

Lisa Polzien, Angela Baljuls, Marco Albrecht, +2

Journal of Biological Chemistry

ApoptosisImmunologyCell DeathCancer BiologyTumor Biology +16

Tyr728 in the Kinase Domain of the Murine Kinase Suppressor of RAS 1 Regulates Binding and Activation of the Mitogen-activated Protein Kinase Kinase

Claudia Sibilski, Thomas D. Mueller, Laxmikanth Kollipara, +4

Journal of Biological Chemistry

The Tumor Suppressor DiRas3 Forms a Complex with H-Ras and C-RAF Proteins and Regulates Localization, Dimerization, and Kinase Activity of C-RAF

Angela Baljuls, Mattias Beck, Ayla Oenel, +5

Journal of Biological Chemistry

Complex FormationMembrane SkeletonCancer BiologyEpigeneticsTumor Biology +20