Tong Chen

Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody

Xiaoxi Zhang, Tong Chen, Victor Li et al. · Analytical Biochemistry · 2022 · 34 citations

Engineering, Analytical Instrumentation, Bioanalysis +14

Imaged capillary isoelectric focusing (icIEF) tandem high resolution mass spectrometry for charged heterogeneity of protein drugs in biopharmaceutical discovery

Xiaoxi Zhang, Teresa Kwok, Mike Zhou et al. · Journal of Pharmaceutical and Biomedical Analysis · 2022 · 29 citations

Protein Drugs, Drug Target, Biochemistry +11

Fractionation and online mass spectrometry based on imaged capillary isoelectric focusing (icIEF) for characterizing charge heterogeneity of therapeutic antibody

Teresa Kwok, Mike Zhou, Anna Schaefer et al. · Analytical Methods · 2022 · 26 citations

Biological Mass Spectrometry, Charge Heterogeneity, Protein Charge Heterogeneity +25

Imaged capillary isoelectric focusing tandem high-resolution mass spectrometry using nano electrospray ionization (ESI) for protein heterogeneity characterization

Teresa Kwok, She Lin Chan, Matthew Courtney et al. · Analytical Biochemistry · 2023 · 18 citations

Microscopy, Biological Mass Spectrometry, Ion Mobility Spectrometry +16

High‐efficient characterization of complex protein drugs by imaged capillary isoelectric focusing with high‐resolution ampholytes

Teresa Kwok, She Lin Chan, Mike Zhou et al. · Separation Science Plus · 2022 · 15 citations

Engineering, High‐resolution Ampholytes, Biomedical Engineering +24