Benoît Tyl

Genetic drug target validation using Mendelian randomisation

Amand F. Schmidt, Chris Finan, María Gordillo‐Marañón et al. · Nature Communications · 2020 · 605 citations · Full text

Life Sciences, Biostatistics, Genetics +17

The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation

John W. Ford, J. Milnes, Saïd El Haou et al. · Heart Rhythm · 2015 · 71 citations · Full text

Medicine, Cardiology, Pharmacology +17

Insulin-like growth factor-binding protein-7 (IGFBP7) links senescence to heart failure

Liyong Zhang, David Smyth, Mohammad Al‐Khalaf et al. · Nature Cardiovascular Research · 2022 · 63 citations · Full text

Life Sciences, Cardiology, Molecular Biology +17

Identifying subtypes of heart failure from three electronic health record sources with machine learning: an external, prognostic, and genetic validation study

Amitava Banerjee, Ashkan Dashtban, Suliang Chen et al. · The Lancet Digital Health · 2023 · 61 citations · Full text

Computing, Cardiology, Health Informatics +17

Lack of Significant Effect of Bilastine Administered at Therapeutic and Supratherapeutic Doses and Concomitantly With Ketoconazole on Ventricular Repolarization: Results of a Thorough QT Study (TQTS) With QT‐Concentration Analysis

Benoît Tyl, Meriam Kabbaj, Sara M. Azzam et al. · The Journal of Clinical Pharmacology · 2011 · 60 citations

Medicine, Pharmacology, Pharmacotherapy +16