Diego García Jiménez

Designing Soluble PROTACs: Strategies and Preliminary Guidelines

Diego García Jiménez, Matteo Rossi Sebastiano, Maura Vallaro et al. · Journal of Medicinal Chemistry · 2022 · 81 citations · Full text

PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery

Giuseppe Ermondi, Diego García Jiménez, Giulia Caron · Molecules · 2021 · 44 citations · Full text

Building Blocks, Drug Target, Molecular Biology +21

Exploring the chemical space of orally bioavailable PROTACs

Giulia Apprato, Vasanthanathan Poongavanam, Diego García Jiménez et al. · Drug Discovery Today · 2024 · 44 citations · Full text

Pharmaceutical Science, Drug Target, Medicinal Chemistry +17

Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs

Diego García Jiménez, Maura Vallaro, Matteo Rossi Sebastiano et al. · Journal of Medicinal Chemistry · 2023 · 36 citations · Full text

Rational Control of Molecular Properties Is Mandatory to Exploit the Potential of PROTACs as Oral Drugs

Giuseppe Ermondi, Diego García Jiménez, Matteo Rossi Sebastiano et al. · ACS Medicinal Chemistry Letters · 2021 · 35 citations · Full text

Drug Target, Permeability Assessment, Medicinal Chemistry +16