Neutrophils escort circulating tumour cells to enable cell cycle progression

Barbara M. Szczerba, Francesc Castro-Giner, Marcus Vetter, +13

Nature

Tumor BiologyOncologyGranulocyteMedicineImmunology +4

Single-cell mutation identification via phylogenetic inference

Jochen Singer, Jack Kuipers, Katharina Jahn, +1

Nature Communications

Lambda: the local aligner for massive biological data

Hannes Hauswedell, Jochen Singer, Knut Reinert

Bioinformatics

Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation

Steffen Boettcher, C. Matthias Wilk, Jochen Singer, +13

Blood

Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers

Ariane Leoni Hofmann, Jonas Behr, Jochen Singer, +5

BMC Bioinformatics

Exome sequencing of healthy phenotypic extremes links TROVE2 to emotional memory and PTSD

Angela Heck, Annette Milnik, Vanja Vukojević, +22

Nature Human Behaviour

PsychopathologyPsychiatryExome SequencingNeurobiological FactorHealthy Phenotypic Extremes +8

NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis

Jochen Singer, Hans‐Joachim Ruscheweyh, Ariane Leoni Hofmann, +19

Bioinformatics

A Comprehensive Analysis of Primer IDs to Study Heterogeneous HIV-1 Populations

David Seifert, Francesca Di Giallonardo, Armin Töpfer, +5

Journal of Molecular Biology

Genetic EpidemiologyGenomicsHigh Throughput SequencingViral EvolutionHuman Retrovirus +21

SwissMTB: establishing comprehensive molecular cancer diagnostics in Swiss clinics

Franziska Singer, Anja Irmisch, Nora C. Toussaint, +11

BMC Medical Informatics and Decision Making

Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma

Christos Dimitrakopoulos, Sravanth K. Hindupur, Marco Colombi, +11

BMC Genomics