Doris R. Siwak

A module of negative feedback regulators defines growth factor signaling

Ido Amit, Ami Citri, Tal Shay et al. · Nature Genetics · 2007 · 494 citations

Life Sciences, Cell Biology, Molecular Biology +13

Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition

Olga K. Mirzoeva, Debopriya Das, Laura M. Heiser et al. · Cancer Research · 2009 · 389 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

Nathan T. Ihle, Robert Lemos, Peter Wipf et al. · Cancer Research · 2008 · 274 citations · Full text

Medicine, Oncology, Pharmacology +17

Curcumin‐induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IκB kinase and nuclear factor κB activity and are independent of the B‐Raf/mitogen‐activated/extracellular signal‐regulated protein kinase pathway and the Akt pathway

Doris R. Siwak, Shishir Shishodia, Bharat B. Aggarwal et al. · Cancer · 2005 · 236 citations · Full text

Medicine, Oncology, Pharmacology +13

Src activation regulates anoikis in human colon tumor cell lines

T. Christopher Windham, Nila U. Parikh, Doris R. Siwak et al. · Oncogene · 2002 · 212 citations

Medicine, Molecular Biology, Oncology +14