Concepedia

Author

Alessio Fiascarelli

Sapienza University of RomeORCID

Also Known As

A Fiascarelli, Alessio Fiascarelli

44

Publications

502

Citations

9

H-Index

35

Concepts

All Affiliations

Sapienza University of RomeInstitute of Molecular Biology and PathologyDiscovery InstituteUniversity of PittsburghMenarini Group (Italy)
AF

About

Alessio Fiascarelli is an author at Sapienza University of Rome specializing in medicine, biochemistry, and cancer metabolism.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

304

2

Biochemistry

4

4

266

3

Cell Biology

3

3

223

4

Public Health

1

1

35

5

Biomolecular Engineering

1

1

46

Alessio Fiascarelli

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9

Publications

479

Citations

9

H-Index

YearCitations

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation

Alessio Paone, Marina Marani, Alessio Fiascarelli,

Cell Death and Disease

2014

130

How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

Giorgio Giardina, Paolo Brunotti, Alessio Fiascarelli,

FEBS Journal

2015

98

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells

Marina Marani, Alessio Paone, Alessio Fiascarelli,

Oncotarget

2015

55

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming

Alessandro Paiardini, Angela Tramonti, Doug Schirch,

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

2016

46

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models

Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano,

Haematologica

2020

38

Screening and In Vitro Testing of Antifolate Inhibitors of Human Cytosolic Serine Hydroxymethyltransferase

Alessandro Paiardini, Alessio Fiascarelli, Serena Rinaldo,

ChemMedChem

2015

36

Molecular mechanism of PdxR – a transcriptional activator involved in the regulation of vitamin B<sub>6</sub> biosynthesis in the probiotic bacterium <i>Bacillus clausii</i>

Angela Tramonti, Alessio Fiascarelli, Teresa Milano,

FEBS Journal

2015

35

MEN1309/OBT076, a First-In-Class Antibody–Drug Conjugate Targeting CD205 in Solid Tumors

Giuseppe Merlino, Alessio Fiascarelli, Mario Bigioni,

Molecular Cancer Therapeutics

2019

27

Model‐based prediction of effective target exposure for <scp>MEN1611</scp> in combination with trastuzumab in <scp>HER2</scp>‐positive advanced or metastatic breast cancer patients

Elena M. Tosca, Elisa Borella, Chiara Piana,

CPT Pharmacometrics & Systems Pharmacology

2023

14

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