Alessio Fiascarelli

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation

Alessio Paone, Marina Marani, Alessio Fiascarelli et al. · Cell Death and Disease · 2014 · 130 citations · Full text

Apoptosis, Cell Death, Cancer Biology +20

How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

Giorgio Giardina, Paolo Brunotti, Alessio Fiascarelli et al. · FEBS Journal · 2015 · 98 citations · Full text

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells

Marina Marani, Alessio Paone, Alessio Fiascarelli et al. · Oncotarget · 2015 · 55 citations · Full text

Cancer Biology, Tumor Biology, Cancer Cell Biology +18

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming

Alessandro Paiardini, Angela Tramonti, Doug Schirch et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2016 · 46 citations

Aldehyde Dehydrogenase, Mitochondrial Function, Biochemistry +11

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models

Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano et al. · Haematologica · 2020 · 38 citations · Full text

Immunology, Immunoediting, Immunotherapy +16