Jeffrey Hung

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles et al. · Nature · 2018 · 5.5K citations

Life Sciences, Immunology, Oncology +16

Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

Claudia X. Dominguez, Sören Müller, Shilpa Keerthivasan et al. · Cancer Discovery · 2019 · 846 citations

Medicine, Cancer Biology, Oncology +13

A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

Felipe de Sousa e Melo, Antonina V. Kurtova, Jonathan M. Harnoss et al. · Nature · 2017 · 792 citations

Medicine, Cancer Biology, Oncology +16

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade

Romain Banchereau, Avantika S. Chitre, Alexis Scherl et al. · Journal for ImmunoTherapy of Cancer · 2021 · 147 citations · Full text

Medicine, Immunology, Oncology +17

Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors

Alessandra Castiglioni, Yagai Yang, Katherine Williams et al. · Nature Communications · 2023 · 90 citations · Full text

Life Sciences, Immunology, Oncology +17