Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype

Franco Aversa, Antonio Tabilio, Andrea Velardi, +15

New England Journal of Medicine

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, +17

Blood

Full Haplotype-Mismatched Hematopoietic Stem-Cell Transplantation: A Phase II Study in Patients With Acute Leukemia at High Risk of Relapse

Franco Aversa, Adelmo Terenzi, Antonio Tabilio, +14

Journal of Clinical Oncology

Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum

Franco Aversa, Antonio Tabilio, Adelmo Terenzi, +6

Blood

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

Mauro Di Ianni, Loredana Ruggeri, Franca Falzetti, +15

Blood

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia

Enrico Tiacci, Jae H. Park, Luca De Carolis, +38

New England Journal of Medicine

Mesenchymal cells recruit and regulate T regulatory cells

Mauro Di Ianni, Beatrice Del Papa, Maria De Ioanni, +5

Experimental Hematology

T-regulatory CellImmunologyMesenchymal Cells RecruitEpithelial-mesenchymal InteractionsAutoimmunity +4

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

Cristina Cunha, Mauro Di Ianni, Silvia Bozza, +15

Blood

Characterization of Mitochondrial and Extra-mitochondrial Oxygen Consuming Reactions in Human Hematopoietic Stem Cells

Cláudia Piccoli, Roberto Ria, Rosella Scrima, +6

Journal of Biological Chemistry

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

Maria Paola Martelli, Valentina Pettirossi, Christian Thiede, +20

Blood