Concepedia

Alice Ke

AK

20

Publications

740

Citations

15

H-Index

2013

Active since

Affiliations

Simcyp (United Kingdom)(Current)

Eli Lilly (United States)

Certara (United States)

Center for Drug Evaluation and Research

Integra LifeSciences (United States)

Alice Ke is an author at Simcyp (United Kingdom) specializing in medicine, pharmacokinetics, and pharmacokinetic modeling.

ORCID

Top concepts

Publications per year

2013–2023

20

Publications

20

Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19

Alice Ke, Srikanth C. Nallani, Ping Zhao et al. · British Journal of Clinical Pharmacology · 2013 · 109 citations · Full text

Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein

J. William Higgins, Jing Bao, Alice Ke et al. · Drug Metabolism and Disposition · 2013 · 92 citations · Full text

A Physiologically Based Pharmacokinetic Model to Predict Disposition of CYP2D6 and CYP1A2 Metabolized Drugs in Pregnant Women

Alice Ke, Srikanth C. Nallani, Ping Zhao et al. · Drug Metabolism and Disposition · 2013 · 86 citations · Full text

Itraconazole and Clarithromycin as Ketoconazole Alternatives for Clinical CYP3A Inhibition Studies

Alice Ke, M J Zamek-Gliszczynski, J. William Higgins et al. · Clinical Pharmacology & Therapeutics · 2014 · 57 citations

Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6

Alice Ke, Zoe Barter, K Rowland‐Yeo et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 49 citations · Full text

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