Michaël Prakesch - Concepedia

Author

Michaël Prakesch

Ontario Institute for Cancer Research ORCID

Also Known As

M Prakesch, M. Prakesch, Michael A. Prakesch, Michael Prakesch, Michaël Prakesch, Prakesch, M.

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Ontario Institute for Cancer Research University of Toronto Steacie Institute for Molecular Sciences Centre National de la Recherche Scientifique Lunenfeld-Tanenbaum Research Institute

About

Michaël Prakesch is an author at Ontario Institute for Cancer Research specializing in natural sciences, organic chemistry, and biomolecular engineering.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	10	10	449
2	Biomolecular Engineering	8	8	315
3	Engineering	6	6	151
4	Medicine	5	5	323
5	Biochemistry	4	4	221

Michaël Prakesch

Publications

860

Citations

H-Index

Page 1

	Year	Citations
Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors Mário Sanches, Nicole M. Duffy, Manisha Talukdar, Nature Communications Molecular PharmacologyAldehyde DehydrogenaseBiochemistryMedicineNatural Sciences	2014	130
Functional characterization of a PROTAC directed against BRAF mutant V600E Ganna Posternak, Xiaojing Tang, Pierre Maisonneuve, Nature Chemical Biology Natural SciencesProtein BiosynthesisBraf Mutant V600eMolecular BiologyProteomics	2020	127
Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells Natalie Grinshtein, Alessandro Datti, Mayumi Fujitani, Cancer Research GliomaTumor BiologyNeuro-oncologyCell RegulationReceptor Tyrosine Kinase	2011	98
PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma Yael Babichev, Leah Kabaroff, Alessandro Datti, Journal of Translational Medicine	2016	52
The Propargylic Route as a Short and Versatile Entry to Optically Active Monofluorinated Compounds Michaël Prakesch, Danielle Grée, René Grée Accounts of Chemical Research Asymmetric CatalysisPropargylic RouteOptical MaterialsEngineeringOptical Properties	2002	41
A drug discovery platform to identify compounds that inhibit EGFR triple mutants Punit Saraon, Jamie Snider, Yannis Kalaidzidis, Nature Chemical Biology Drug TargetMedicineDrug DiscoveryRational Drug DesignDrug Discovery Platform	2020	37
The propargylic route as efficient entry to monofluoro and gem-difluoro compounds: mechanistic considerations Michaël Prakesch, E. Kerouredan, Danielle Grée, Journal of Fluorine Chemistry HalogenationPropargylic RouteAlkene MetathesisFluorous SynthesisOrganic Chemistry	2004	36
The discovery of small molecule chemical probes of Bcl-XL and Mcl-1 Michaël Prakesch, A. Yu. Denisov, Marwen Naïm, Bioorganic & Medicinal Chemistry Molecular RecognitionMolecular CharacterizationBiochemistryNatural SciencesMolecular Biology	2008	36
Synthesis of New Optically Active Propargylic Fluorides and Application to the Enantioselective Synthesis of Monofluorinated Analogues of Fatty Acid Metabolites Michaël Prakesch, Danielle Grée, René Grée The Journal of Organic Chemistry Fatty Acid MetabolitesEngineeringAlkene MetathesisBiochemistryNatural Sciences	2001	36
Use of Kinase Inhibitors to Correct ΔF508-CFTR Function Agata M. Trzcińska-Daneluti, Leo Nguyen, Chong Jiang, Molecular & Cellular Proteomics Molecular PharmacologyFibrosisMolecular PhysiologySignal TransductionSignaling Pathway	2012	33

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