Tobias Noeske

Mitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural Modification

Daniel J. Warner, Hongming Chen, Louis‐David Cantin et al. · Drug Metabolism and Disposition · 2012 · 85 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Predicting Compound Selectivity by Self‐Organizing Maps: Cross‐Activities of Metabotropic Glutamate Receptor Antagonists

Tobias Noeske, Britta C. Sasse, Holger Stark et al. · ChemMedChem · 2006 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Ligand-Based Target Prediction with Signature Fingerprints

Jonathan Alvarsson, Martin Eklund, Ola Engkvist et al. · Journal of Chemical Information and Modeling · 2014 · 46 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

In silico approaches in organ toxicity hazard assessment: Current status and future needs in predicting liver toxicity

Arianna Bassan, Vinícius M. Alves, Alexander Amberg et al. · Computational Toxicology · 2021 · 43 citations · Full text

Pharmacy, Bioinformatics, Toxicology +17

Design and Optimization of Pyrazinecarboxamide-Based Inhibitors of Diacylglycerol Acyltransferase 1 (DGAT1) Leading to a Clinical Candidate Dimethylpyrazinecarboxamide Phenylcyclohexylacetic Acid (AZD7687)

Jonas G. Barlind, Udo Bauer, Alan M. Birch et al. · Journal of Medicinal Chemistry · 2012 · 37 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17