Patrick Chames

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

Julianne Smith, Sylvestre Grizot, Sylvain Arnould et al. · Nucleic Acids Research · 2006 · 314 citations · Full text

Engineering, Reverse Genetics, Genetics +23

Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets

Sylvain Arnould, Patrick Chames, Christophe Perez et al. · Journal of Molecular Biology · 2005 · 181 citations

Engineering, Oligonucleotide, Genetic Engineering +11

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR

Ralph A. Willemsen, M. E. M. Weijtens, C. P. M. Ronteltap et al. · Gene Therapy · 2000 · 169 citations

Cell Therapy, Cancer Immunosurveillance, Immunology +8

Oriented conjugates of single-domain antibodies and quantum dots: toward a new generation of ultrasmall diagnostic nanoprobes

Alyona Sukhanova, Klervi Even-Desrumeaux, Aymric Kisserli et al. · Nanomedicine Nanotechnology Biology and Medicine · 2011 · 161 citations

Nanoparticles, Nanomedicine, Engineering +13

Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library

Patrick Chames, Simon E. Hufton, Pierre G. Coulie et al. · Proceedings of the National Academy of Sciences · 2000 · 118 citations · Full text