Seth Weir

Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma

Kent Riemondy, Sujatha Venkataraman, Nicholas Willard et al. · Neuro-Oncology · 2021 · 131 citations · Full text

Childhood Mb Subgroups, Immunogenetics, Functional Genomics +15

scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy

Jennifer K. Ocasio, Benjamin Babcock, Daniel Malawsky et al. · Nature Communications · 2019 · 107 citations · Full text

p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2

Erica W. Cloer, Priscila F. Siesser, Emily Cousins et al. · Molecular and Cellular Biology · 2018 · 67 citations · Full text

Reductive Stress, Signal Transduction, Anchor Mutations +13

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

Tigist Y. Tamir, Brittany M. Bowman, Megan J. Agajanian et al. · Journal of Cell Science · 2020 · 31 citations · Full text

Gain-of-function Genetic Screen, Genetics, Nrf2 Transcription Factor +29

A conditional mouse expressing an activating mutation in <scp><i>NRF2</i></scp> displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

Brittany M. Bowman, Stephanie A. Montgomery, Travis P. Schrank et al. · The Journal of Pathology · 2020 · 24 citations · Full text