Akihiko Mizoroki

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Active since

2008

Affiliations

Akihiko Mizoroki is an author at Chugai Pharma (United States) specializing in structure-based pharmacophore design, structure-guided lead discovery, and structure-based de novo design.

Publications per year

2008–2024

Publications

Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease

Yuu Okura, Yuri Ikawa-Teranishi, Akihiko Mizoroki et al. · Nature Communications · 2023 · 15 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Structure-based discovery of a novel non-peptidic small molecular inhibitor of caspase-3

Junichi Sakai, Atsushi Yoshimori, Yasuyo Nose et al. · Bioorganic & Medicinal Chemistry · 2008 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A bispecific antibody targeting HLA-DQ2.5-gluten peptides potently blocks gluten-specific T cells induced by gluten ingestion in patients with celiac disease

Melinda Y. Hardy, Lee Henneken, Amy K. Russell et al. · Clinical Immunology · 2024 · 11 citations · Full text

Life Sciences, Immunology, Pathobiology +17

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