Concepedia

Amandine Chefson

AC

Statistics

Publications

11

Citations

374

H-Index

10

Active since

2006

Affiliations

Merck Canada Inc. (Canada)(Current)

McGill University

United States Military Academy

Amandine Chefson is an author at Merck Canada Inc. (Canada) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

2006–2025

11

Publications

11

Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses

Bernard Côté, Jason D. Burch, Ernest Asante‐Appiah et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 101 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +14

Identification of <b>RP-6685</b>, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ

Monica Bubenik, P. Mäder, Philippe Mochirian et al. · Journal of Medicinal Chemistry · 2022 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Replacement of Natural Cofactors by Selected Hydrogen Peroxide Donors or Organic Peroxides Results in Improved Activity for CYP3A4 and CYP2D6

Amandine Chefson, Jin Zhao, Karine Auclair · ChemBioChem · 2006 · 53 citations

Life Sciences, Biochemistry, Chemistry +16

CYP3A4 Activity in the Presence of Organic Cosolvents, Ionic Liquids, or Water‐Immiscible Organic Solvents

Amandine Chefson, Karine Auclair · ChemBioChem · 2007 · 43 citations

Life Sciences, Biochemistry, Chemistry +17

Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)

W. Cameron Black, Abbas Abdoli, Xiuli An et al. · Journal of Medicinal Chemistry · 2024 · 27 citations · Full text

Medicine, Oncology, Pharmacology +15

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