Michinari Hirata

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.

Kiyoshi Yoshida, Tetsuya Taga, M. Saito et al. · Proceedings of the National Academy of Sciences · 1996 · 641 citations

Life Sciences, Genetics, Molecular Biology +16

Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis

T Yamagami, Haruo Sugiyama, Kazushi Inoue et al. · Blood · 1996 · 261 citations

Medicine, Molecular Genetics, Oncology +16

CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory

Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu et al. · Proceedings of the National Academy of Sciences · 2022 · 204 citations · Full text

Life Sciences, Immunology, Oncology +17

Heparin-Binding EGF-Like Growth Factor Is a Promising Target for Ovarian Cancer Therapy

Shingo Miyamoto, Michinari Hirata, Ayano Yamazaki et al. · Cancer Research · 2004 · 185 citations

Life Sciences, Cell Biology, Oncology +15

A Dual Signaling Cascade That Regulates the Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor

Toshiyuki Umata, Michinari Hirata, Tsuyoshi Takahashi et al. · Journal of Biological Chemistry · 2001 · 107 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16