Clark R. Restrepo

An acetylation switch controls TDP-43 function and aggregation propensity

Todd J. Cohen, Andrew Hwang, Clark R. Restrepo et al. · Nature Communications · 2015 · 343 citations · Full text

Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Krista J. Spiller, Clark R. Restrepo, Tahiyana Khan et al. · Nature Neuroscience · 2018 · 329 citations

Amyotrophic Lateral Sclerosis, Tdp-43 Proteinopathy, Medicine +10

Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo

Sílvia Porta, Yan Xu, Clark R. Restrepo et al. · Nature Communications · 2018 · 246 citations · Full text

Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy

Krista J. Spiller, Claudia Cheung, Clark R. Restrepo et al. · Journal of Neuroscience · 2016 · 97 citations · Full text

Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice

Krista J. Spiller, Tahiyana Khan, Myrna A. Dominique et al. · Neurobiology of Disease · 2018 · 49 citations · Full text

Matrix Metalloproteinase 9, Molecular Neuroscience, Motor Neurons +9