Onyi Irrechukwu

Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

Lorna Ewart, Skyler A. Briggs, Christopher V. Carman et al. · Communications Medicine · 2022 · 279 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters

Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani et al. · Drug Metabolism and Disposition · 2015 · 136 citations

Medicine, Pharmacokinetics, Pharmacology +17

Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications

Lorna Ewart, Skyler A. Briggs, Christopher V. Carman et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 36 citations · Full text

Pharmacy, Biotechnology, Toxicology +15

AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules

Mohan Rao, Vahid Nassiri, Cristóbal Alhambra et al. · Chemical Research in Toxicology · 2023 · 36 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development

Lindsay Tomlinson, Diane Ramsden, Sofia Batista Leite et al. · Advanced Biology · 2023 · 26 citations · Full text

Pharmacy, Pharmacology, Biopharmaceutics +12