Harris Ioannidis

The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods

Barbara Zdrazil, Eloy Félix, Fiona Hunter et al. · Nucleic Acids Research · 2023 · 1.2K citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +17

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

Alessio De Simone, C. Georgiou, Harris Ioannidis et al. · Chemical Science · 2018 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

Jordi Juárez‐Jiménez, Arun A. Gupta, Gogulan Karunanithy et al. · Chemical Science · 2020 · 33 citations · Full text

Natural Sciences, Biochemistry, Biophysics +17

Alchemical Free Energy Calculations and Isothermal Titration Calorimetry Measurements of Aminoadamantanes Bound to the Closed State of Influenza A/M2TM

Harris Ioannidis, Antonios Drakopoulos, Christina Tzitzoglaki et al. · Journal of Chemical Information and Modeling · 2016 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Interpreting Thermodynamic Profiles of Aminoadamantane Compounds Inhibiting the M2 Proton Channel of Influenza A by Free Energy Calculations

Nadine Homeyer, Harris Ioannidis, Felix Kolarov et al. · Journal of Chemical Information and Modeling · 2015 · 29 citations

Natural Sciences, Medicinal Chemistry, Pharmacology +17