Rie Sonamoto

Selective inhibition of the kinase DYRK1A by targeting its folding process

Isao Kii, Yuto Sumida, Toshiyasu Goto et al. · Nature Communications · 2016 · 86 citations · Full text

Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ

Rie Sonamoto, Isao Kii, Y. Koike et al. · Scientific Reports · 2015 · 38 citations · Full text

Target Kinase, Molecular Pharmacology, Natural Sciences +15

DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain

Samira Abu Jhaisha, Esti Widowati, Isao Kii et al. · Scientific Reports · 2017 · 38 citations · Full text

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis

So Masaki, Isao Kii, Yuto Sumida et al. · Bioorganic & Medicinal Chemistry · 2015 · 29 citations

Potent Inhibitor, Medicine, Drug Discovery +8