EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

Kexin Xu, Zhenhua J. Wu, Anna C. Groner, +19

Science

Histone ModificationsEpigenetic ChangeCancer BiologyEpigeneticsTumor Biology +20

Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1

Changmeng Cai, Housheng Hansen He, Sen Chen, +8

Cancer Cell

Androgen ReceptorNatural SciencesHormonal ReceptorMolecular BiologyLysine-specific Demethylase 1 +5

Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

Changmeng Cai, Sen Chen, Patrick Kwok‐Shing Ng, +9

Cancer Research

Tumor BiologyAndrogen ReceptorUrologyEndocrine-related CancerMedicine +12

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

Changmeng Cai, Hongyun Wang, Housheng Hansen He, +12

Journal of Clinical Investigation

Rapid Induction of Androgen Receptor Splice Variants by Androgen Deprivation in Prostate Cancer

Ziyang Yu, Sen Chen, Adam G. Sowalsky, +5

Clinical Cancer Research

SOX9 drives WNT pathway activation in prostate cancer

Fen Ma, Huihui Ye, Housheng Hansen He, +9

Journal of Clinical Investigation

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Eddy J. Chen, Adam G. Sowalsky, Shuai Gao, +14

Clinical Cancer Research

Reactivation of Androgen Receptor–Regulated <i>TMPRSS2:ERG</i> Gene Expression in Castration-Resistant Prostate Cancer

Changmeng Cai, Hongyun Wang, Youyuan Xu, +2

Cancer Research

Androgen ReceptorTranscriptional RegulationSignal TransductionHormonal ReceptorGene Regulation +13

Lysine-Specific Demethylase 1 Has Dual Functions as a Major Regulator of Androgen Receptor Transcriptional Activity

Changmeng Cai, Housheng Hansen He, Shuai Gao, +13

Cell Reports

Has Dual FunctionsLysine 4Epigenetic ChangeGeneticsMolecular Biology +17

ETV1 Is a Novel Androgen Receptor-Regulated Gene that Mediates Prostate Cancer Cell Invasion

Changmeng Cai, Chen-Lin Hsieh, Josephat Omwancha, +4

Molecular Endocrinology

Androgen ReceptorTranscriptional RegulationSystems BiologyGene Microarray StudiesMedicine +7