Paul J. Barrett

α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

Roberto Di Maio, Paul J. Barrett, Eric K. Hoffman et al. · Science Translational Medicine · 2016 · 587 citations · Full text

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

Paul J. Barrett, Yuanli Song, Wade D. Van Horn et al. · Science · 2012 · 469 citations · Full text

The Backbone Dynamics of the Amyloid Precursor Protein Transmembrane Helix Provides a Rationale for the Sequential Cleavage Mechanism of γ-Secretase

Oxana Pester, Paul J. Barrett, Daniel Hornburg et al. · Journal of the American Chemical Society · 2012 · 74 citations · Full text

Protein Chemistry, Sequential Cleavage Mechanism, Backbone Dynamics +15

Nonspecificity of Binding of γ-Secretase Modulators to the Amyloid Precursor Protein

Andrew J. Beel, Paul J. Barrett, Paul D. Schnier et al. · Biochemistry · 2009 · 40 citations · Full text

Lmpg Micelles, Protein Secretion, Protein Function +13

Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles

Jonathan P. Schlebach, Paul J. Barrett, Charles Day et al. · Biochemistry · 2016 · 24 citations · Full text

Liquid-disordered Domains, Proteinlipid Interaction, Molecular Biology +16