Chun Yew Fong

BET inhibitor resistance emerges from leukaemia stem cells

Chun Yew Fong, Omer Gilan, Enid Y.N. Lam et al. · Nature · 2015 · 548 citations · Full text

Medicine, Cancer Biology, Oncology +14

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy

Chong Chyn Chua, Andrew W. Roberts, John Reynolds et al. · Journal of Clinical Oncology · 2020 · 190 citations

Medicine, Oncology, Pharmacotherapy +17

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

Charles C. Bell, Katie Fennell, Yih-Chih Chan et al. · Nature Communications · 2019 · 180 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

Mark A. Dawson, Emma Gudgin, Sarah J. Horton et al. · Leukemia · 2013 · 175 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Functional interdependence of BRD4 and DOT1L in MLL leukemia

Omer Gilan, Enid Y.N. Lam, Isabelle Becher et al. · Nature Structural & Molecular Biology · 2016 · 124 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +10