Douglas D. Kolstoe

The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.

John R. Silber, Michael S. Bobola, A. Blank et al. · PubMed · 2002 · 149 citations

Medicine, Molecular Biology, Oncology +16

O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics.

John R. Silber, M S Bobola, Saadi Ghatan et al. · PubMed · 1998 · 146 citations

Medicine, Cancer Biology, Oncology +6

O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy.

John R. Silber, A. Blank, M S Bobola et al. · PubMed · 1999 · 135 citations

Medicine, Cancer Biology, Oncology +17

Establishment and characterization of four human medulloblastoma-derived cell lines.

G. Evren Keles, M S Berger, J. Srinivasan et al. · PubMed · 1995 · 103 citations

Veterinary Medicine, Genetics, Oncology +14

Lack of the DNA repair protein O6-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary human brain tumors.

John R. Silber, A. Blank, M S Bobola et al. · Proceedings of the National Academy of Sciences · 1996 · 78 citations

Medicine, Molecular Biology, Oncology +17